There is a wealth of angst on the interlink, detailing the challenges of taking this path.

Be aware with these distros, that you will face a challenge, and posssibly a conflict between the Jack audio server, and the pulseaudio domestic server that is packaged with these distros by default. Ubuntu, Fedora, and Debian are desktop variants that have versions for making music. That's a tough one, that depends on how much effort you put in. 'which is the fastest linux audio distro?' Tuxphobia, i'll try and answer at least some of your questions. But don't get fooled and think you can only have 16! Just create additional midi ports in LS and you can have as many as you like. * When working with program changes: open the same number of sample channels in LinuxSampler as midi channels/tracks in Rosegarden. And yes, you need to tell every sample channel what midimap to use (just as you need to load the correct bank for a device in Rosegarden). * How many midimaps do you have? LinuxSampler can have several maps arbitrary assigned to sample channels (which in turn can be arbitrary connected to midi-ports and -channels), while Rosegarden can only handle one map per device, so it's usually easier to stick to only one big midimap used by every channel. Now do open a channel for each bank in fantasia to give me access to the samples in Rosegarden and tell each channel what midimap to use? Ok so after a long time of figuring this out I have the following:

Midi map with absynth 5